A Nigerian version of the popular children’s show “Sesame Street” is set to debut on May 21, and will tackle weighty issues such as HIV/AIDS discrimination, hygienic practices and ways to cope with death.

The show, which will be re-titled “Sesame Square,” is a collaboration between Sesame Street International and USAID/Nigeria. More than three years in the making and funded by a nearly $4 million budget, the show will air on Nigeria’s National Television Authority every Saturday and Sunday, according to the Associated Press.

Among its characters, the show will feature two unique muppets: Kami, an HIV-positive girl and Zobi, a blue muppet with an affinity for yams. The educational program targets children, parents and caregivers.

“The television series is committed to the principle that all children deserve a chance to learn and grow; to be prepared for school; to better understand the world and each other; to think, dream and discover and to reach their highest potential,” USAID said in a statement.

The partnership between the two groups will produce 78 half-hour episodes, and provide 81,000 activity books, 5,400 guides for caregivers and 240 storyboards. Materials will be distributed to orphans and other vulnerable children through an outreach program. Training will be made available for 5,000 caregivers.

The makers of Sesame Street have also begun a new effort to provide natural disaster preparedness education for children and families. Sesame Street Workshop recently collaborated with the Chinese foundations to “distribut emergency response content,” in the wake of recent earthquakes there. The organization has also worked with Haiti, India and Bangladesh in their outreach efforts.