By Dan Crippen
Earlier this year, when the administration proposed deep cuts to the National Institutes of Health, lawmakers from both parties swiftly and rightly pushed back. Slashing medical research funding, they recognized, would jeopardize the discovery of breakthrough treatments that patients desperately need.

Thatโs why itโs baffling that many of the same lawmakers who voted to protect NIH funding are now cheering President Trumpโs plan to impose โmost favored nationโ (MFN) price controls on drugs, a policy that could cause greater harm to innovation.
At first glance, MFN may sound reasonable. It would link U.S. drug prices to the lowest prices paid in other wealthy countries. Supporters argue this would bring down prices at home and encourage drugmakers to raise prices abroad, easing the burden on American patients who pay more than their international counterparts. Itโs fair to expect other nations to contribute more.
However, MFN pricing wouldnโt force other countries to pay more. In most overseas markets, governments set drug prices unilaterally. Companies canโt simply raise them. Instead of leveling the playing field, MFN would slash revenues for pharmaceutical manufacturers in their largest market, with no way to recover those losses.
Faced with steep U.S. revenue declines, drugmakers would have no choice but to cut spending. Research and development would be among the first targets.
According to a University of Chicago study, MFN-style price controls could lead to a 60 percent reduction in drug research and development over the next 18 years, resulting in more than 340 fewer drugs reaching the market.
That loss would be devastating โ especially given the enormous health challenges we face. In 2024, one in three deaths in the United States was caused by heart disease or stroke. More than 38 million Americans had diabetes. Obesity affected 42 percent of adults. Alzheimerโs deaths rose 141 percent between 2000 and 2021. And every year, 1.7 million Americans are diagnosed with cancer.
Lawmakers were right to question NIH budget cuts that would have put future cures at risk. At a recent Senate hearing, a senior member observed: โIf research is underway, you at least have the hope that maybe thereโll be a cure, maybe in the lifetime of someone. How can you walk away from that?โ
Lawmakers should take the same stance on MFN pricing. It poses an even greater threat by undermining the private investment essential to drug development.
If policymakers are serious about protecting patients and promoting medical progress, they must resist the allure of MFN and pursue more thoughtful reforms, ones that lower costs without sacrificing innovation.
Dan Crippen is a former director of the Congressional Budget Office. This column originally appeared at DC Journal. The opinions expressed in this commentary are those of the writer and not necessarily those of the AFRO.

